Canthaxanthin Retinopathy: A Long-term Observation

University of Cologne

Status: Completed

Conditions: Canthaxanthin Retinopathy

Study type: Observational

Funder types: Other

Identifiers

NCT01128062

AHARMS-8310

Details and patient eligibility

About

Canthaxanthine is a naturally occurring carotenoid that has been a popular over-the-counter oral artificial tanning agent in Europe, Canada, and Australia since 1979. It is also used at low dosage as a food-colouring agent and as a therapeutic agent for photosensitivity disorders such as erythropoietic protoporphyria. Canthaxanthin retinopathy was first described in 1982 by Cortin et al. In Germany the office of the federal board of health refused the permit for oral tanning agents containing canthaxanthine in 1985. At that time the long-term course of the disease was not known. 25 years later the investigators did these long-term follow-up examinations.

Enrollment: 35 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients using oral tanning agents for at least 2 months.
• patients of 18 years or older

Exclusion criteria

• none.