Capillary Lactate and Transfusion Needs

Grenoble Alpes University Hospital Center (CHU)

Status: Completed

Conditions: Trauma

Treatments: Other: Capillary lactate level

Study type: Observational

Funder types: Other

Identifiers

NCT01793428

2012-19

Details and patient eligibility

About

13% of injured normotensive patients arriving in emergency unit need mass blood-transfusion of six or more units of packed Red Blood Cells. It is currently difficult to predict the need for such a mass blood-transfusion. Indeed hemoglobin point of care testing (hemocue) and blood pressure can be normal during the first hours despite intensive bleeding.

It's well known that blood or arterial lactate measures correlate with trauma severity but these measures are not available in a pre-hospital setting. The investigators want to test whether capillary lactate measures also correlate with trauma severity and can therefore predicts earlier transfusion needs.

Enrollment: 120 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult admitted in vital emergency unit
• Severe trauma
• normotensive (Systolic Blood Pressure >90mmHg)
• patient subjected to capillary haemoglobin and glucose measurements
• patient beneficiary of social security

Exclusion criteria

• pregnant woman
• liver deficiency
• pre-hospital transfusion
• hypothermia below 35°C
• protected persons according to the law
• Nor epinephrine > 0.1gamma/kg/min

Trial design

120 participants in 1 patient group

Injured patient admitted in vital emergency unit

Treatment:

Other: Capillary lactate level