Capnometry-Assisted Breathing Training for COPD (CATCH)

NYU Langone Health

Status and phase: Completed; Phase 2

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Device: Pulmonary Rehabilitation (PR); Device: Capnometry-Assisted Training for COPD to Slow the Breath (CATCH)

Study type: Interventional

Funder types: Other

Identifiers

NCT03457103

17-01672

Details and patient eligibility

About

Capnometry-Assisted Breathing Training for COPD (CATCH) is a behavioral intervention that aims to promote optimal, self-regulated, mindful breathing. A portable capnometer is used in-session to provide continuous visual feedback of Respiratory Rate (RR), End-Tidal Carbon Dioxide Tension (ETCO2), and breathing pattern. The tailored CATCH intervention will emphasize a slow, quiet, regular, nasal breathing pattern, as well as pursed lips breathing (PLB). CATCH is once weekly for 6 weeks, for a total of 6 sessions; each session is approximately 60 minutes long. The principal investigator will implement the CATCH intervention. The principal investigator will implement the CATCH intervention. Patients will use the Address Stress app on a smart phone or computer tablet as part of their home breathing exercises.

Enrollment: 31 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• over 40 years of age
• has COPD documented in their electronic medical record, as defined by FEV1/FVC of < 0.70 on pulmonary function testing (spirometry), or as shown on a chest CT
• Can maintain oxygen saturation (SaO2) ≥ 90% on room air at rest
• Is medically cleared to participate in NYULMC's outpatient pulmonary rehabilitation program
• English speaking. Pregnant patients will not be enrolled in the study

Exclusion criteria

• Requires 24-hour supplemental oxygen
• Has cognitive impairment as measured by ≤23/30 on the Mini Mental State Examination (MMSE)
• Is actively being treated for lung cancer (E.g. with chemotherapy or upcoming surgery)
• Has morbid obesity (BMI > 40)
• Is currently smoking
• Has unstable cardiac disease defined by a history of a myocardial infarction in the past 3 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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31 participants in 2 patient groups

CATCH Group

Experimental group

Description:

A portable capnometer (CapnoTrainer, Better Physiology, Cheyenne, WY) will be used in-session to provide continuous visual feedback of RR, ETCO2, rhythm, and depth of breathing, and ratio of inspirations to expiration. CATCH will be once weekly for 6 weeks, for a total of 6 sessions; each session will be approximately 60 minutes duration. The principal investigator will implement the CATCH intervention

Treatment:

Device: Capnometry-Assisted Training for COPD to Slow the Breath (CATCH)

Device: Pulmonary Rehabilitation (PR)

Control Group

Active Comparator group

Description:

Pulmonary Rehabilitation (PR). Patients in both treatment groups will participate in a 10-week (16 - 20 sessions) comprehensive PR program.

Treatment:

Device: Pulmonary Rehabilitation (PR)