Capsule Endoscopy in Iron Deficiency Anaemia (WCE-IDA)

Vastra Gotaland Region

Status: Not yet enrolling

Conditions: Iron Deficiency Anemia; Bowel Cancer

Treatments: Procedure: Endoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT06219395

281233

Details and patient eligibility

About

This project aim to investigate whether wireless capsule endoscopy(WCE) has a similar diagnostic yield as conventional endoscopy in detecting the cause of iron deficiency anemia (IDA)

Full description

IDA is common and 90-95% of cases are caused by bleeding from ulcers, tumours or vascular malformations in the oesophagus, stomach, duodenum, small intestine or the large bowel.Bleeding from more than one localisation is common.

International guidelines recommend bidirectional endoscopy(gastro- and colonoscopy) to detect and treat the source of bleeding.

Our hypothesis is that WCE is non-inferior to the combination of gastroscopy and colonoscopy in locating GI-bleeding and that complete examinations will be achieved in ≥90% of the examinations.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Referred to flexible endoscopy for a verified Iron Deficiency Anaemia

Exclusion criteria

• Unwillingness to participate
• Not able to provide informed consent
• Not understanding the instructions
• Severe cardio-vascular disease New York Heart Association III-IV
• Symptoms of bowel obstruction/previous bowel obstruction
• Bowel surgery except for end to end anastomosis in the colon
• Pregnancy

Trial design

100 participants in 1 patient group

Iron deficiency anaemia

Description:

Persons 18-85 years with Iron deficiency anaemia referred for gastroscopy and colonoscopy

Treatment:

Procedure: Endoscopy