Capturing Parkinson's Disease Medication Side Effects During Daily Activities

Great Lakes NeuroTechnologies

Status: Completed

Conditions: Parkinson's Disease; Dyskinesia

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01429207

1R43NS071882-01A1

Details and patient eligibility

About

The purpose of the study is to test whether body-worn wireless motion sensors can measure dyskinesias (involuntary movements caused by medications) in individuals with Parkinson disease (PD) independent of voluntary activity being performed and other PD motor symptoms (e.g. tremor).

Enrollment: 15 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of probable or definite idiopathic Parkinson Disease with motor fluctuations that include dyskinesias after taking their usual dose of levodopa/carbidopa

Exclusion criteria

• Antipsychotic medications (including quetiapine and clozapine)
• Coexisting neurologic disease such as stroke or dementia
• Lacking capacity for informed consent
• Residing in a nursing home
• comorbid non-neurologic illnesses that impacts the ability to perform the study tasks
• Implantable defibrillators