Carbachols Headache-inducing Effect and Changes in Cerebral Blood Flow in Migraine Patients

Danish Headache Center

Status: Completed

Conditions: Headache

Treatments: Drug: Carbachol

Study type: Interventional

Funder types: Other

Identifiers

NCT00564408

HC20070049

Details and patient eligibility

About

The purpose of this study is to test if carbachol infusion induces headache in migraine subjects as well as intra- and extra-cerebral vasodilatation.

Full description

To test if infusion of Carbachol induces headache in 12 migraine subjects as well as intra- and extra-cerebral vasodilatation in a double-blinded study

Enrollment: 12 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Migraine without aura
• Weight 50-100 kg

Exclusion criteria

• Other significant diseases
• Migraine 5 days prior to experiment

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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12 participants in 1 patient group

I

Experimental group

Treatment:

Drug: Carbachol