Carbohydrate-Protein Supplementation During Endurance Running

T

The University of Tennessee, Knoxville

Status

Completed

Conditions

Supplementation During Endurance Performance

Treatments

Dietary Supplement: CHO-CHO, PLA, CHO, CHO-P
Dietary Supplement: CHO-P, CHO-CHO, PLA, CHO
Dietary Supplement: CHO, CHO-P, CHO-CHO, PLA
Dietary Supplement: PLA, CHO, CHO-P, CHO-CHO

Study type

Interventional

Funder types

Other

Identifiers

NCT00972387
University of TN IRB 7959-B

Details and patient eligibility

About

The purpose of this study is to assess whether the greater performance benefits from ingesting carbohydrate-protein supplements during endurance running, in comparison to the traditionally used carbohydrate supplement, is attributed to the extra calories contained in the carbohydrate-protein supplement or the presence of protein.

Full description

The purpose of this study is to determine whether the performance benefits from consuming a carbohydrate-protein (CHO-P) supplement, such as Accelerade, during endurance exercise, as opposed to the traditionally used carbohydrate (CHO) supplement, such as Gatorade, are attributed to the extra calories in the CHO-P supplement or the presence of protein alone in comparison to CHO supplements. Numerous studies comparing CHO and CHO-P supplements on endurance performance have found contradicting results in terms of CHO-P supplementation and performance benefits. While physiological mechanisms have been proposed as to why the CHO-P supplements elicit greater performance, research has yet to determine why some studies have found this, especially while other studies have found no performance benefits from CHO-P supplementation. This inconsistency in research may be due to the caloric difference between supplements tested; due to the addition of protein, the CHO-P supplement contains more calories per serving than the CHO supplement. As a result, this study will be comparing 4 different supplements during endurance exercise, a CHO-P supplement, CHO supplement, a double carbohydrate supplement (CHO-CHO), and a placebo (PLA). The CHO and CHO-P supplement will be matched for CHO content, whereas the CHO-P and CHO-CHO supplements will be matched for total caloric content. Participants will be asked to run four 12-mile runs on 4 separate occasions, approximately 7-10 days apart, and will be blinded to supplement content and order of supplement administration among trials. The 12-mile run will elicit an exercise bout greater than 60 minutes, which is relevant when supplementing exercise with CHO or CHO-P. Performance will be assessed via time it takes to complete both the 12-mile run and the 1.6 mile maximal effort at the end of the run.

Enrollment

12 patients

Sex

Male

Ages

18 to 55 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Males aged 18-55 years old BMI in the healthy range, 18.5-24.9 Run 45-90+ minutes at least 4 days per week Engage in running this frequency and duration for at least 4 weeks prior to the phone screen Engage in a run consisting ≥10 miles in length for at least 2-4 occasions per month for at least 2 months prior to the phone screen No previous history of heart conditions No shortness of breath or chest pain experienced during running or daily activities No bone or joint problems experienced during running or daily activities

Exclusion criteria

Females and males under the age of 18 and over the age of 55 Females are excluded from this study in order to prevent any potential factors associated with the female athlete triad and endurance performance outcomes. BMI below 18.5 or greater than 24.9 Does not meet all other criteria listed (#3-6) Allergies to products containing milk, soy, or aspartame Severe allergies to eggs, wheat, tree nuts, fish, crustaceans, shellfish products (Accelerade, the CHO-P supplement, is made in a facility that processed these products) Refusal to consume any of the supplements, and/or extreme dislike of the supplements Refusal to complete the specified distance of the time trials

Trial design

Primary purpose

Other

Allocation

Randomized

Interventional model

Factorial Assignment

Masking

Single Blind

12 participants in 4 patient groups

Order 1
Active Comparator group
Description:
Supplement order for each time trial run, 1-4 respectively: CHO, CHO-P, CHO-CHO, PLA
Treatment:
Dietary Supplement: CHO, CHO-P, CHO-CHO, PLA
Order 2
Active Comparator group
Description:
Supplement order for each time trial run, 1-4 respectively: CHO-P, CHO-CHO, PLA, CHO
Treatment:
Dietary Supplement: CHO-P, CHO-CHO, PLA, CHO
Order 3
Active Comparator group
Description:
Supplement order for each time trial run, 1-4 respectively: CHO-CHO, PLA, CHO, CHO-P
Treatment:
Dietary Supplement: CHO-CHO, PLA, CHO, CHO-P
Order 4
Active Comparator group
Description:
Supplement order for each time trial run, 1-4 respectively: PLA, CHO, CHO-P, CHO-CHO
Treatment:
Dietary Supplement: PLA, CHO, CHO-P, CHO-CHO

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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