Carbohydrate Use During and Following Exercise (CHO-use)

Maastricht University Medical Centre (MUMC)

Status: Unknown

Conditions: Carbohydrate Oxidation and Glycogen Utilization During and Following Exercise

Treatments: Dietary Supplement: Carbohydrate ingestion

Study type: Interventional

Funder types: Other

Identifiers

NCT01709617

12-3-048

Details and patient eligibility

About

Carbohydrates are an integral component of sports nutrition. Providing carbohydrate (CHO) during exercise delays the onset of fatigue and improves exercise performance by maintaining high rates of CHO oxidation. Traditionally, glucose, or glucose polymers have been the preferential CHO source found in sports drinks. However, during the intestinal absorption of large amounts of glucose (>1.2 g/min), sodium-dependent glucose transporters (SGLT1) may become fully saturated, potentially limiting the rate of exogenous CHO oxidation. In an effort to evade this limitation, research has suggested using multiple transportable carbohydrates in the composition of sports drinks. Multiple transportable carbohydrates are combinations of simple sugars that use different intestinal transporters during the absorption process. Ingesting multiple transportable carbohydrates may enhance the capacity for total intestinal CHO absorption, leading to an increase in the rate of exogenous CHO oxidation. Our purpose will be to examine the disaccharide sucrose in it's ability to provide exogenous fuel during and following prolonged exercise.

Enrollment: 17 estimated patients

Sex: Male

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Male
• 18 - 40 years of age
• Endurance trained cyclist/triathlete
• VO2 max ≥ 50 ml/kg/min
• BMI < 25 kg/m2

Exclusion criteria

• Use of medication
• Smoking

Trial design

17 participants in 3 patient groups

Glucose-glucose

Experimental group

Description:

Glucose ingestion

Treatment:

Dietary Supplement: Carbohydrate ingestion

Glucose-Fructose

Active Comparator group

Description:

glucose-fructose ingestion

Treatment:

Dietary Supplement: Carbohydrate ingestion

disaccharide

Active Comparator group

Description:

Disaccharide ingestion

Treatment:

Dietary Supplement: Carbohydrate ingestion