Carbon Dioxide Insufflation (CO2) and Warm Water Infusion (WWI) Versus Standard Air Insufflation (AI) for Unsedated Colonoscopy

Valduce Hospital

Status: Completed

Conditions: Unsedated Colonoscopy; CO2 Colonoscopy; Warm Water

Treatments: Procedure: CO2; Procedure: Warm water

Study type: Interventional

Funder types: Other

Identifiers

NCT01259583

CO2-01

Details and patient eligibility

About

Due to the increasing demand for colonoscopy in clinical practice, great interest has recently renewed for unsedated colonoscopy. Both Carbon dioxide Insufflation (CO2) and Warm Water Infusion (WWI) have been advocated to improve patient tolerance for colonoscopy as compared to standard Air Insufflation (AI). This study is aimed at evaluating the performance of the above techniques versus AI in unsedated patients.

Enrollment: 341 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• adult outpatients willing to undergo colonoscopy without routine initial sedation

Exclusion Criteria:

• refuse to initiate colonoscopy without routine sedation
• inadequate bowel preparation
• incapacity to give informed consent

Trial design

341 participants in 2 patient groups

CO2

Experimental group

Description:

CO2 insufflation instead air insufflation in unsedated colonoscopy

Treatment:

Procedure: CO2

Warm Water irrigation

Experimental group

Description:

warm water irrigation during the insertion phase of colonoscopy

Treatment:

Procedure: Warm water