Carbon Dioxide Versus Air Insufflation in Oesophago-gastro-duodenoscopy (OGD)

Norwegian Department of Health and Social Affairs

Status: Completed

Conditions: Pain

Treatments: Procedure: CO2 insufflation

Study type: Interventional

Funder types: Other

Identifiers

NCT00627211

STHF Gastro BS1

Details and patient eligibility

About

Comparison on the effect on patient pain and discomfort by using CO2 instead of air for insufflation during gastroscopy.

Full description

To achieve a satisfactory examination of the GI tract it needs to be distended during endoscopic procedures. After the examinations many patients complain of abdominal pain and discomfort. This pain has been substantially reduced by substituting room air with CO2 in both colonoscopies and ERCPs. The use of CO2 during colonoscopy has become routine practice at many endoscopy centers.

In our study we will test the hypothesis that abdominal pain after gastroscopies also can be reduced by substituting room air with CO2.

Enrollment: 107 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for OGD at the outpatient clinic of Telemark Hospital

Exclusion criteria

• Age <18
• Inability to give an informed concent
• Unsatisfactory norwegian language skills
• Patients not willing to participate
• COPD with dyspnoea NYHA 3-4

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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107 participants in 2 patient groups

Room air insufflation

No Intervention group

Description:

Air used for insufflation during gastroscopy to expand the lumen for inspection of the mucosal lining. This is current standard procedure, i.e. no experimental intervention.

CO2 insufflation

Experimental group

Description:

CO2 used for insufflation during gastroscopy to expand the lumen for inspection of the mucosal lining. This is not standard procedure and therefore experimental intervention.

Treatment:

Procedure: CO2 insufflation