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CARbon monoxidE intoxiCatiOn in Korea: Prospective Cohort (CARE CO Cohort)

W

Wonju Severance Christian Hospital

Status

Enrolling

Conditions

Carbon Monoxide Poisoning
Therapy
Complications
Prognostic Factors
Neurologic Deficits
Image, Body
Myocardial Injury

Treatments

Procedure: Hyperbaric oxygen therapy
Diagnostic Test: Cardiac MRI

Study type

Observational

Funder types

Other

Identifiers

NCT04490317
CARE CO cohort

Details and patient eligibility

About

This prospective cohort study enrolls subjects who experience carbon monoxide (CO) poisoning. The purpose of the study is to evaluate therapeutic effects of various treatments and short and long-term outcomes in CO poisoned patients. In addition, complications of brain and heart susceptible to CO are investigated through various ways and the association between complications and the patient's prognosis is also investigated. All subjects will be regularly monitored by physicians participating in this study.

Full description

This prospective cohort study enrolls subjects who experience CO poisoning. The purpose of the study is to evaluate therapeutic effects of various treatments, including hyperbaric oxygen therapy (HBO), therapeutic hypothermia (TH), and additional drugs, and short and long-term outcomes, such as neurocognitive sequelae or mortality, in CO poisoned patients. In addition, complications of brain and heart susceptible to CO are investigated through a variety of ways, such as magnetic resonance image (MRI), computed tomography (CT), ultrasound, and laboratory test, and the association between various complications and the patient's prognosis is also investigated. All subjects will be regularly monitored by physicians participating in this study.

Enrollment

1,500 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Acute CO poisoning

Exclusion criteria

  • Declined to enrollment in the study

Trial design

1,500 participants in 1 patient group

Acute CO poisoning
Description:
A diagnosis of CO poisoning is made according to medical history and carboxyhemoglobin \>5% (\>10% in smokers).
Treatment:
Diagnostic Test: Cardiac MRI
Procedure: Hyperbaric oxygen therapy

Trial contacts and locations

1

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Central trial contact

Yong Sung Cha, MD

Data sourced from clinicaltrials.gov

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