Cardiac Arrest Extra Corporeal Oxygenation Membrane (CAREECMO)

Central Hospital, Nancy, France

Status: Unknown

Conditions: Cardiopulmonary Resuscitation; Extracorporeal Life Support; Cardiac Arrest; Advanced Cardiac Life Support

Treatments: Procedure: Fast track access to vaECMO

Study type: Interventional

Funder types: Other

Identifiers

NCT03352999

2016-A01873-48.

Details and patient eligibility

About

French guidelines for Cardio Pulmonary Resuscitation (CPR) consider Extra-Corporeal Life Support (ECLS) as one option in Refractory out-of hospital Cardiac Arrest (ROHCA) patients with a no-flow less than five minutes and absence of spontaneous circulation 30 minutes after initiation of advanced CPR. Duration of both pre-CPR arrest (no-flow) and of CPR (low-flow) have been systematically highlighted as crucial prognostic factors in all observational studies focused on ROHCA.

In order to shorten the time to ECLS initiation, the most recent European Resuscitation Council guidelines recommend, in eligible ROHCA patients, a fast track access to ECLS implantation.

CHRU Nancy elaborated an operational strategy which was designed to improve the enrolment of eligible ROHCA patients and to reduce the delay time between recognition and ECLS initiation.

The objective of the present register was to assess prospectively the impact of this new operational strategy over a 5 years period.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Witnessed out-of-hospital cardiac arrest
• in qualified geographical locations
• No Return of spontaneous circulation (ROSC) after 10 min of CPR
• No Flow <1 min

Exclusion criteria

• Apparent obvious comorbidities
• Patient < 18 yo
• Pregnancy
• Patient under protective supervision

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

50 participants in 1 patient group

ROHCA rescued by vaECMO

Other group

Description:

Patients experiencing a ROHCA despite advanced CPR and finally rescued with a va ECMO device.

Treatment:

Procedure: Fast track access to vaECMO