Cardiac Arrhythmias and Dysfunction in the Pediatric Burn Patient

Shriners Hospitals for Children

Status: Terminated

Conditions: Cardiac Dysfunction

Treatments: Diagnostic Test: Echocardiogram

Study type: Interventional

Funder types: Other

Identifiers

NCT03085420

CIN1604

Details and patient eligibility

About

The purpose of this study is to collect information about how often an abnormal heart beat happens in children who have been burned.

Full description

The investigators hope to learn the following:

• If heart arrhythmias are more common in children with a large burn injury than in children with a small burn injury.
• The difference in development of a heart arrhythmia after a large burn injury by comparing information from children with large burns who do and do not develop a heart arrhythmia.
• A better understanding of the length of a hospital stay, the number of operations, and the number of care complications in patients with heart arrhythmias after a burn injury.

Enrollment: 10 patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Pediatric burn patients from age 0 - 18 who have sustained a burn injury will be eligible for this study.

Group 1 will consist of patients with ≥30% TBSA burn injury. Group 2 will consist of patients with <30% TBSA burn injury who develop a cardiac abnormality.

Exclusion criteria

Patients with pre-existing cardiac disorder, desquamative skin disorders and electrical injury.

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

≥30% TBSA burn injury

Experimental group

Description:

For patients in Group 1 with ≥30% TBSA, a baseline Echocardiogram (ECHO) will be obtained approximately one week from admission and monthly (+/- 1 week) or at an interval determined by cardiology during the acute inpatient stay. ECHO tests will be discontinued after 3 negative exams or when discontinued by cardiology, whichever comes first.

Treatment:

Diagnostic Test: Echocardiogram

<30% TBSA burn injury

No Intervention group

Description:

For patients in Group 2 with \<30% TBSA and presence of a cardiac abnormality standard clinical care appropriate for the type of arrhythmia will be followed.