Cardiac Magnetic Resonance in Acute Myocarditis

University Hospital Bonn (UKB)

Status: Completed

Conditions: Myocarditis

Treatments: Other: Cardiac magnetic resonance scan

Study type: Observational

Funder types: Other

Identifiers

NCT02299856

150/13.2

Details and patient eligibility

About

Cardiac magnetic resonance (MR) is an established noninvasive diagnostic tool for detection of acute myocarditis. Diagnosis of myocarditis at 1.5T is currently made with the help of the Lake Louise Criteria (two of three criteria have to be positive in order to establish the diagnosis). Although these criteria are accepted and widely used in clinical routine, several disadvantages exist. Newer parameters like myocardial T1 and T2 mapping, extracellular volume fraction (ECV) and myocardial strain analysis have the potential to complement or even replace some of the Lake Louise Criteria and further enhance the diagnostic performance of cardiac MR in patients suspected of having acute myocarditis. The aim of our study is to evaluate the diagnostic performance of a comprehensive cardiac MR protocol in patients with acute myocarditis.

Enrollment: 84 patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• No past medical history of cardiac disease.
• No cardiovascular risk factors (e.g. diabetes or hypertension)

Exclusion criteria

• Contraindications for cardiac MR

Trial design

84 participants in 2 patient groups

Myocarditis

Description:

Patients with strong clinical evidence for acute myocarditis (recent infection, elevated troponin and white blood cell count).

Treatment:

Other: Cardiac magnetic resonance scan

Healthy Controls

Description:

Healthy volunteers without any signs of cardiac disease.

Treatment:

Other: Cardiac magnetic resonance scan