Cardiac Magnetic Resonance in Children With Muscular Dystrophy

Cooperative International Neuromuscular Research Group (CINRG)

Status: Completed

Conditions: Becker Muscular Dystrophy; Limb Girdle Muscular Dystrophy; Duchenne Muscular Dystrophy

Study type: Observational

Funder types: NETWORK; NIH

Identifiers

NCT01081080

PITT0110

Details and patient eligibility

About

This protocol will exploit novel state of the art cardiovascular magnetic resonance techniques to examine important changes in the heart in children with muscular dystrophy. The purpose of this study is to compare cardiac magnetic resonance (CMR) with the collected cardiac outcome data obtained in protocol: PITT1109 - Cardiac Outcome Measures in Children with Muscular Dystrophy.

Enrollment: 20 estimated patients

Sex: All

Ages: 8 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participant enrolled in the CINRG study: PITT1109 - Cardiac Outcome Measures in Children with Muscular Dystrophy

Exclusion criteria

• Pregnant woman (when uncertain, participants will undergo urine testing) or lactating women

• Decompensated congestive heart failure (unable to lie flat during CMR)

• Impaired renal excretory function (calculated Glomerular Filtration Rate less than 30mL/min)

• Contra-indications to Magnetic Resonance Imaging:

  • Cardiac pacemaker or implantable defibrillator
  • Cerebral aneurysm clip
  • Neural stimulator
  • Metallic ocular foreign body
  • Harrington-rod
  • Any implanted device (i.e. insulin pump, drug infusion device)
  • Claustrophobia
  • Metal shrapnel or bullet