Cardiac Magnetic Resonance Predictors of Outcome of Rhythm Control in Patients with Atrial Fibrillation/Flutter

Assiut University

Status: Not yet enrolling

Conditions: Rhythm Monitoring

Study type: Observational

Funder types: Other

Identifiers

NCT06758895

CMR in rythm control

Details and patient eligibility

About

evaluate the impact of various features in CMR on the mid-term/long-term success rate of rhythm control for paroxysmal atrial fibrillation/flutter .

Full description

• Atrial fibrillation/flutter are widely prevalent.
• Reported antiarrhythmic drug efficacy to restore & maintain sinus rhythm is 52% which is far from optimal.
• On the other hand, 5-year arrhythmia-free survival after catheter ablation was previously reported to be 63%.
• Therefore, there is a need for better characterization of the underlying atrial substrate, to improve treatment outcomes in terms of efficacy and safety

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age>18 years.
• Patients undergoing successful cardioversion (pharmacologic or electric) for atrial fibrillation/flutter, OR symptomatic patients with paroxysmal atrial fibrillation/flutter scheduled for trans-catheter ablation.
• Index cardioversion OR Index ablation procedure.

Exclusion criteria

• LA thrombus on TEE or CMR.
• Contraindications to CMR.
• Contraindications to Gd-based contrast.