Cardiac Outcome Measures in Children With Muscular Dystrophy

Cooperative International Neuromuscular Research Group (CINRG)

Status: Completed

Conditions: Becker Muscular Dystrophy; Duchenne Muscular Dystrophy; Limb Girdle Muscular Dystrophy

Study type: Observational

Funder types: NETWORK; NIH

Identifiers

NCT01066455

PITT1109

Details and patient eligibility

About

The purpose of the research study is to evaluate different cardiac measures that are obtained by echocardiographic tests in patients with muscular dystrophy.

Full description

The research study will include 50 participants aged 8 to 18 years old (before 18th birthday) with Duchenne, Becker, or autosomal recessive limb-girdle (specifically: LGMD 2C-2F and 2I) muscular dystrophies.

Participants will be seen in one of five Cooperative International Neuromuscular Research Group (CINRG) centers located in the United States.

All study assessments will be completed in the same day and include reviewing past medical and surgical history, collecting vital signs, collecting cardiac measures through echocardiographic tests.

Enrollment: 48 patients

Sex: All

Ages: 8 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants must be between the ages of 8 and 18 years old
• Confirmed diagnosis of muscular dystrophy (DMD, BMD, or LGMD 2C-2F and 2I)

Exclusion criteria

• Investigator assessment of inability to comply with protocol
• History of a congenital cardiac defect or other cardiac disease unrelated to muscular dystrophy