Cardiac Output Assessment by Using Saline Contrast Injection (CardioLog)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Echocardiography

Treatments: Other: contrast assessment of cardiac output (CO); Other: cardiac Doppler technique

Study type: Observational

Funder types: Other

Identifiers

NCT04310904

PI2018_843_0057

Details and patient eligibility

About

Cardiac output (CO) assessment is one of the cornerstone of hemodynamic evaluation in ICU patients. CO is usually measured using invasive methods or non-invasive methods. Thermodilution is considered as the gold standard for CO assessment. Cardiac Doppler as well demonstrated to be accurate but needs manipulations and good knowledge and skills. The investigators developed a new technique using injection of agitated saline solution to evaluate CO without any manual measurement and then observer independent.

Full description

The investigators decided to conduct a prospective observational study to compare contrast assessment of CO and cardiac Doppler technique. Patients hospitalized in ICU will be included if they need a trans esophageal echocardiographic evaluation and a research of intra cardiac shunt (using a saline contrast test). Patients with Swan Ganz catheter will be included as well. Cardiac output will be measured using cardiac Doppler. Simultaneously, 4.5 ml of saline with 0.5 ml of air will be agitated to have a contrast solution. This solution will be injected as usual and echocardiographic imaging will be recorded. These imaging will be analyzed off-line and CO will be calculated with an algorithm previously developed and compared with the reference method. In case of swan ganz catheter, the cardiac output will be also measured using the thermodilution technique.

Enrollment: 65 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all ICU patients intubated/ventilated with a central line and an arterial catheter who need trans esophageal echocardiography examination with a saline contrast test.

Exclusion criteria

• patients under 18 years old
• pregnant patients
• moribund patients

Trial design

65 participants in 1 patient group

ICU cardiac output (CO) assessment patients

Description:

all ICU patients intubated/ventilated with a central line and an arterial catheter who need trans esophageal echocardiography examination with a saline contrast test.

Treatment:

Other: contrast assessment of cardiac output (CO)

Other: cardiac Doppler technique