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Cardiac, Pulmonary and Diaphragm Sonography for the Early Diagnosis of the Different Etiologies Underlying Failure of Weaning From Mechanical Ventilation (WEAN US)

U

University Hospital Center (CHU) Dijon Bourgogne

Status

Unknown

Conditions

Following Heart or Abdominal Surgery
Mechanical Ventilation

Study type

Observational

Funder types

Other

Identifiers

NCT03261440
KLEIN 2016

Details and patient eligibility

About

Weaning patients off ventilation in an ICU is sometimes difficult, because of three major inter-related etiologies: impaired lung, heart and diaphragm function. In this context, ultrasonography during tests to wean patients off ventilation could make it possible to diagnose cardiac dysfunction, a loss of pulmonary aeration or diaphragm dysfunction and thus reduce the number of failures at extubation.

The study will be carried out in 100 patients on mechanical ventilation following abdominal or heart surgery, who will have echocardiography, and pulmonary and diaphragm ultrasonography.

Enrollment

100 estimated patients

Sex

All

Ages

60+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients on mechanical ventilation for at least 48 hours
  • Age ≥ 60 years
  • Patients who have undergone abdominal or heart surgery

Exclusion criteria

  • Patients with a known neuromuscular disease
  • Patients younger than 60 years
  • Duration of mechanical ventilation <48h
  • Non-surgical patients
  • Patients with severe COPD

Trial contacts and locations

1

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Central trial contact

Belaïd BOUHEMAD

Data sourced from clinicaltrials.gov

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