Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Status: Unknown

Conditions: Cardiac Disease; Blood Transfusion; Hemoglobinemia; Thoracic Surgery

Treatments: Other: Acceptance of blood-transfusions; Other: Non-acceptance of blood-transfusions

Study type: Observational

Funder types: Other

Identifiers

NCT04609228

IIBSP-TRA-2020-36

Details and patient eligibility

About

The primary objective of this study is to analyze mortality after cardiac surgery in blood-transfusion non-acceptors (BTNA), and the secondary one to perform an adjusted comparison with a blood-transfusion acceptors (BTA) matched cohort.

Enrollment: 1,911 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing heart surgery in our hospital from 2009 to June 2020

Exclusion criteria

• Preoperative hemoglobin lower than 120g/L
• EuroSCORE-II higher than 20%
• Heart transplant
• Assist device implantation
• Surgery of acute myocardial infarction-derived complications
• Other emergent cardiac surgeries (acute aortic dissection, heart injuries).

Trial design

1,911 participants in 2 patient groups

Blood-transfusion non-acceptors

Description:

Blood-transfusion non-acceptors

Treatment:

Other: Non-acceptance of blood-transfusions

Blood-transfusion acceptors

Description:

Blood-transfusion acceptors

Treatment:

Other: Acceptance of blood-transfusions