Cardiac T1 Mapping Enables Risk Prediction of LV Dysfunction After Surgery for Aortic Regurgitation

Universitätsklinikum Hamburg-Eppendorf

Status: Completed

Conditions: Aortic Regurgitation

Treatments: Procedure: aortic valve surgery

Study type: Observational

Funder types: Other

Identifiers

NCT05332184

BAV_T1

Details and patient eligibility

About

To assess whether cardiac T1 mapping for detection of myocardial fibrosis enables preoperative identification of patients at risk for early left ventricular dysfunction after surgery of aortic regurgitation.

Full description

We hypothesized that a diffuse interstitial myocardial fibrosis may be present in AR patients who experience early systolic LV dysfunction after aortic valve surgery. We aimed to evaluate the association between preoperative cardiac T1 mapping for detection of myocardial fibrosis and early systolic LV dysfunction after surgery for aortic regurgitation.

Enrollment: 40 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients with severe aortic regurgitation referred for aortic valve surgery were prospectively enrolled in the study.

Exclusion criteria

• history of coronary artery disease
• acute aortic valve disease (i.e., type A aortic dissection or infectious endocarditis)
• common contraindications for MRI such as severe obesity and metallic foreign bodies.

Trial design

40 participants in 1 patient group

Patients prior to aortic valve surgery

Treatment:

Procedure: aortic valve surgery