Cardiology Research Dubrava Prospective Registry (CaRDr)

University Hospital Dubrava

Status: Enrolling

Conditions: Atrial Fibrillation; Acute Coronary Syndrome; Arrhythmias, Cardiac; Heart Failure

Treatments: Other: SGLT-2 inh therapy, CIED implantation, thromboaspiration,

Study type: Observational

Funder types: Other

Identifiers

NCT06090591

DUH-012017

Details and patient eligibility

About

Cardiology Research Dubrava registry is a prospective, single centre registry including patients with acute coronary syndrome with and without ST segment elevation, patients with heart failure who were prescribed with SGLT-2 inhibitors, patients implanted with TAVI, patients with venous thromboembolism, patients with pulmonary embolism who underwent thromboaspiration procedure, patients implanted with ICD, CRT and conduction system pacing devices, as well as patients with atrial fibrillation who underwent pulmonary vein isolation and are prescribed with long-term anticoagulation therapy.

Full description

Cardiology Research Dubrava registry is a prospective, single centre registry including patients with acute coronary syndrome with and without ST segment elevation, patients with heart failure who were prescribed with SGLT-2 inhibitors, patients implanted with TAVI, patients with venous thromboembolism, patients with pulmonary embolism who underwent thromboaspiration procedure, patients implanted with ICD, CRT and conduction system pacing devices, as well as patients with atrial fibrillation who underwent pulmonary vein isolation and are prescribed with long-term anticoagulation therapy.

In this long-term follow-up registry we plan to collect data on clinical status, standard laboratory results including lipidogram values, NTproBNP values after specific interventions (in.ex. TAVI implantation, SGLT2inh prescripition), bleeding complications, and every major cardiovascular event, including cardiovascular death and all cause death.

Enrollment: 3,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: patients implanted with CIED, or with VTE, or with ACS or with TAVI -

Exclusion Criteria: non compliance, not undergoing follow-up at this center

Trial design

3,000 participants in 6 patient groups

Acute coronary syndrome - ACS

Description:

patients who were diagnosed with acute coronary syndrome: STEMI, non-STE ACS - NSTEMI and unstable angina, who underwent coronary angiography and were prescribed with optimal medicament therapy

Treatment:

Other: SGLT-2 inh therapy, CIED implantation, thromboaspiration,

Transcatheter aortic valve implantation - TAVI

Description:

patients with aortic stenosis who underwent transcatheter percotaneous implantation of the arteficial aortic valve

Treatment:

Other: SGLT-2 inh therapy, CIED implantation, thromboaspiration,

Venous thromboembolism - VTE

Description:

patients with pulmonary embolism and deep vein thrombosis, with a focus on those who underwent thromboaspiration due to high or medium-high risk pulmonary embolism

Treatment:

Other: SGLT-2 inh therapy, CIED implantation, thromboaspiration,

Heart failure with SGLT2 inhibitor therapy included - HF-SGLT2

Description:

patients with heart failure with reduced, mid-reduced and preserved systolic function who were prescribed with a SGLT-2 inhibitor therapy, and other optimal medicament therapy for HF

Treatment:

Other: SGLT-2 inh therapy, CIED implantation, thromboaspiration,

Cardiac implantable electronic device - CIED

Description:

patients who were implanted with a cardiac implantable electronic device: pacemaker, conduction system pacing device, cardioverter-defibrilator or cardiac resynchronization therapy with or without defibrilator option

Treatment:

Other: SGLT-2 inh therapy, CIED implantation, thromboaspiration,

Arrhythmias

Description:

patients who underwent electrophysiology study, including PVI for atrial fibrillation, as well as SVT ablations, and ventricular arrhythmia ablation (both premature ventriclar beats and ventricular tachycardia ablation in ischsmic and non-ischemic cardiomyopathy).