Cardiometabolic Response to a Sodium-bicarbonated Mineral Water

Higher Council for Scientific Research (CSIC)

Status: Completed

Conditions: Dyslipidemia

Treatments: Dietary Supplement: Mineral water

Study type: Interventional

Funder types: Other

Identifiers

NCT02480816

BW-13

Details and patient eligibility

About

The effects of consuming a sodium-bicarbonated mineral water rich in bicarbonate, sodium, chloride, lithium and silicon are studied in humans. The aim of this assay was to determine whether the consumption of this water as part of the usual diet, reduces cardiometabolic risk factors in adult men and women.

Enrollment: 72 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults, men and women >18 and ≤ 45 years
• Total-cholesterol > 200 mg/dL and < 300 mg/dL

Exclusion criteria

• Age <18 and > 45 years
• Total-cholesterol ≥300 mg/dL
• Triglycerides > 250 mg/dL
• Total-cholesterol / HDL-cholesterol > 6
• Being a usual consumer of carbonic mineral water
• BMI < 20 and >30 kg/m2
• Diabetes
• Hypertension or digestive, liver or renal disease
• Eating disorders
• Being under medication that could affect lipid metabolism
• Consumption of functional foods that could affect lipid metabolism (food containing n-3 fatty acids or phytosterols)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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72 participants in 2 patient groups

Bicarbonated mineral water (BW)

Experimental group

Description:

Bicarbonated mineral water

Treatment:

Dietary Supplement: Mineral water

Control mineral water (CW)

Active Comparator group

Description:

Mineral water low in mineral content (control)

Treatment:

Dietary Supplement: Mineral water