Cardiopulmonary Exercise Testing as an Outcome Predictor in Coronary Artery Bypass Surgery

Eduardo Tibirica, MD, PhD

Status: Completed

Conditions: Coronary Artery Disease; Surgery--Complications

Treatments: Diagnostic Test: Cardiopulmonary Exercise Testing

Study type: Interventional

Funder types: Other

Identifiers

NCT03376542

CAAE: 67629917.1.0000.5272

Details and patient eligibility

About

This is a prospective cohort study of patients undergoing coronary artery bypass graft surgery. Prior to surgery, participants will undergo submaximal cardiopulmonary exercise testing on a treadmill. Participants will be followed for one month after surgery to assess mortality and non fatal complications.

Full description

Coronary artery bypass surgery (CABG) is a complex and expensive procedure with great potential for morbidity and mortality. Preoperative evaluation is of paramount importance to optimize results. There is much evidence about the benefits of the cardiopulmonary exercise testing (CPET) in the evaluation of preoperative risk in non-cardiac surgeries. Thus, it is important to evaluate the relationship between parameters obtained in the CPET and the outcomes after cardiac surgery, especially CABG.

This is a prospective cohort study in which participants undergo submaximal CEPT on a treadmill prior to CABG. Participants will be followed up for one month after surgery to assess mortality and non fatal complications. It is expected that poor cardiopulmonary fitness is related to worse outcomes in CABG, as already observed in other cardiac pathologies and in non-cardiac surgery.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing coronary artery bypass grafting surgery at the National Institute of Cardiology, Ministry of Health, Rio de Jnaeiro, Brazil.

Exclusion criteria

• Angina CCS IV, heart failure NYHA IV, inability to walk on a treadmill, severe left main coronary artery lesion.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Cardiopulmonary exercise testing

Experimental group

Description:

All patients included in the study will perform cardiopulmonary exercise testing prior to surgery

Treatment:

Diagnostic Test: Cardiopulmonary Exercise Testing