Cardiorespiratory Performance in Diabetic Elderly

Universidade Federal de Pernambuco

Status: Completed

Conditions: Diabetics Patients; Hypertensive Patients

Treatments: Other: Biochemical analysis; Other: Cardiorespiratory performance assessment with ergospirometry test

Study type: Interventional

Funder types: Other

Identifiers

NCT01757080

etiene

Details and patient eligibility

About

OBJECTIVE: To analyze the influence of lipid control during a cardiorespiratory exercise test in two subgroups. DESIGN: Parallel trial study. PARTICIPANTS: The sample consisted of 40 elderly people, male and female, divided into two groups: 20 hypertensive (G1; 68.50 ±5.85 years) and 20 diabetic-hypertensive (G2; 68.95 ±6.79 years). MEASUREMENTS: Nutritional status; glucose and lipid controls - postprandial glucose (PPG), triglycerides (TG), total cholesterol (TC), low density lipoprotein (LDL-C), very low density lipoprotein (VLDL-C), high density lipoprotein (HDL-C); blood pressure, and cardiorespiratory performance. The significance level was set at p<0.05.

Enrollment: 40 patients

Sex: All

Ages: 60 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 60-years-old or above
• diagnosis of hypertension and/or T2DM for at least 2 years
• member active of the hypertension and diabetes mellitus program
• be on optimized drug therapy for more than 3 months
• BMI above 22 kg/m²;
• no heart disease
• non-insulin-dependent,
• sedentary according to the International Physical Activity Questionnaire (IPAQ) and
• functionally independent.

Exclusion criteria

• ergospirometry interrupted by adaptive,
• hemodynamic, and electrocardiographic complications;
• respiratory exchange ratio (R) lower than 1.0 at the end of exertion,
• VE/VCO2 value higher than 34 in the first anaerobic threshold;
• chronic atrial fibrillation;
• neuromuscular,
• orthopedic,
• peripheral vascular,
• pulmonary diseases;
• myocardial infarction within 6 months;
• orthopedic limitation or musculoskeletal pain.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Diabetic-hypertensive elderly

Experimental group

Description:

Biochemical analysis and Cardiorespiratory performance assessment with ergospirometry test

Treatment:

Other: Cardiorespiratory performance assessment with ergospirometry test

Other: Biochemical analysis

Hypertensive elderly

Active Comparator group

Description:

Biochemical analysis and Cardiorespiratory performance assessment with ergospirometry test

Treatment:

Other: Cardiorespiratory performance assessment with ergospirometry test

Other: Biochemical analysis