Cardiovascular Complications and COVID-19 (CovCardioVasc-Study)

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Pulmonary Embolism; Venous Thromboembolism; Acute Coronary Syndrome; Myocarditis; COVID; Deep Vein Thrombosis; Myocardial Infarction

Study type: Observational

Funder types: Other

Identifiers

NCT04335162

20reamedcovid01

Details and patient eligibility

About

Patients with COVID-19 in the Intensive Care Unit (ICU) or hospitalized with severe form have a poor prognosis (almost 30% rate of death). They present often a high cardiovascular risk profile (almost 30% of hypertension and 19% of diabetes). Troponin has been described to be elevated in a high proportion of patients (one fifth of all patients and 50% of non-survivors) suggesting the possibility of cardiomyopathies. High levels of DDimers (81% of non survivors) and fibrin degradation products are also associated with increased risk of mortality suggesting also the possibility of venous thromboembolism. Therefore, screening for cardiomyopathies and venous thromboembolism could represent an important challenge for patients with COVID-19 management.

Enrollment: 198 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All consecutive patients with COVID-19 infection admitted to the ICU or hospitalized because of severe form (eg: hypoxia, orthopnea, pneumonitis, kidney insufficiency) will be included

Exclusion criteria

• Patients under 18 years

Trial design

198 participants in 4 patient groups

Patients with cardiovascular complications

Description:

Patients presenting with cardiomyopathies or venous thromboembolism

Patients without cardiovascular complications

Description:

Patients without cardiomyopathies or venous thromboembolism

Intensive Care Unit patients

Description:

Patients admitted in intensive care unit

Hospital Ward patients

Description:

Patients admitted in hospital ward