Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone Deficiency

Novo Nordisk

Status and phase: Terminated; Phase 4

Conditions: Adult Growth Hormone Deficiency; Growth Hormone Disorder

Treatments: Drug: somatropin

Study type: Interventional

Funder types: Industry

Identifiers

NCT01698944

GHDADULT-1112

Details and patient eligibility

About

This trial is conducted in Europe. The aim of this trial is to investigate the effect of growth hormone on left ventricle morphology and function (systolic and diastolic).

Enrollment: 7 patients

Sex: All

Ages: 12 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult growth hormone deficiency
• At least 2 years without growth hormone treatment

Exclusion criteria

• Supine blood pressure above 160 mmHg systolic or above 100 mmHg diastolic
• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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7 participants in 1 patient group

Somatropin

Experimental group

Treatment:

Drug: somatropin