Cardiovascular Function in Acute Leukemia

Abramson Cancer Center at Penn Medicine

Status: Completed

Conditions: Cardiotoxicity; Leukemia, Myeloid, Acute; Leukemia, Lymphoid, Acute

Treatments: Other: observation only

Study type: Observational

Funder types: Other

Identifiers

NCT03760237

UPCC48418

Details and patient eligibility

About

An observational, prospective study to describe the rates and predictors of cardiovascular events in patients with acute leukemia.

Full description

Patients recently diagnosed with acute leukemia and who will initiating chemotherapy will be enrolled and followed serially with blood collection, echocardiogram, arterial applanation tonometry, and questionnaires for 1 year.

Enrollment: 84 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Older than 18 years of age,
• New diagnosis of untreated acute leukemia (prior treatment for myelodysplastic syndrome or myeloproliferative neoplams or prior treatment with an anthracycline for breast cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma or another diagnosis will be included).
• Signed the informed consent form

Exclusion criteria

• Unable to provide informed consent

Trial design

84 participants in 1 patient group

Acute Leukemia

Description:

Observation only. Patients newly diagnosed with acute leukemia who are scheduled to start treatment with chemotherapy will be enrolled and followed serially with blood collection, echocardiogram, arterial applanation tonometry, and questionnaires for 1 year.

Treatment:

Other: observation only