Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes
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About
The objective of the analysis was to evaluate the relationship between bariatric surgery and cardiovascular outcomes in obese patients with type 2 diabetes. This is a retrospective matched cohort study of patients with diabetes that underwent bariatric surgery at the Cleveland Clinic between 2004-2017. Each bariatric patient was matched to a non-surgical control with obesity and type 2 diabetes in a 1:5 ratio using data from the Electronic Medical Record (EMR). The maximum observation time was 10 years. Cumulative incidence rates for all-cause mortality and cardiovascular events were calculated at years 1, 3, 5, 7 and 10. Kaplan-Meier curves were created for all the outcomes with all-cause mortality considered as a completing risk.
Enrollment
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Inclusion criteria
- Type II diabetes
- 18-80 years old
- BMI>=30
- HBA1c >6.4 OR taking at lease one (1) diabetes medication (insulin or non-insulin)
Exclusion criteria
- History of liver, heart, or lung transplant
- Emergency department admission within 5 days prior
- Cancer diagnosis within 1 year prior
- Any prior ejection fraction <20%
- Non-surgical controls were excluded if they died within 30 days after the index date (date of surgery for the bariatric patients)
- Last follow-up date on or before the index date
Trial design
13,722 participants in 2 patient groups
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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