Cardiovascular Risk and Preventive Care in Prostate Cancer Patients Receiving Radiation and Hormone Therapy

UNC Lineberger Comprehensive Cancer Center

Status: Completed

Conditions: Prostate Cancer

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT02003417

LCCC 1218

Details and patient eligibility

About

This study will evaluate the proportion of prostate cancer patients receiving external beam radiation therapy (EBRT) and androgen deprivation therapy (ADT) with controlled blood sugars (fasting glucose and hemoglobin A1c), blood pressure, and cholesterol profile (total cholesterol, LDL, HDL, triglycerides) at baseline, 3 months, and 12 months after completing radiation treatment. In addition, receipt of guideline-recommended cardiovascular, primary and preventive care as well as patient-reported quality of life and satisfaction with care among these patients will be evaluated at baseline and 12 months.

Enrollment: 101 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically-confirmed, non-metastatic prostate cancer
• Patients who will receive external beam radiation treatment with androgen deprivation therapy (total ADT duration > 3 months) for curative treatment, either in the definitive or post-prostatectomy setting
• Patients who have a primary care provider
• Informed consent obtained and signed
• Ability to read and write English
• Age >= 18
• No mental incompetence which would preclude completion of questionnaires

Exclusion criteria

• Prior cancer, pelvic radiation treatment or chemotherapy
• Patients who do not have a primary care provider
• Prior ADT
• Mental incompetence which would preclude completion of questionnaires
• Unable to read and write English

Trial design

101 participants in 1 patient group

Non-metastatic prostate cancer patients

Description:

Histologically-confirmed, non-metastatic prostate cancer patients who received external beam radiation treatment with androgen deprivation therapy (total ADT duration \> 3 months) for definitive treatment.