Cardiovascular Variability and Heart Rate Response Associated With Obstructive Sleep Apnea (OSAS)

Centre Hospitalier Universitaire de Saint Etienne

Status: Unknown

Conditions: Sleep Apnea, Obstructive

Treatments: Device: standard 24-h ambulatory polysomnography

Study type: Observational

Funder types: Other

Identifiers

NCT03075787

1700176

Details and patient eligibility

About

Obstructive sleep apnea is often associated with microarousals and a stimulation of the sympathetic nervous system. The knowledge of this autonomic activation may help understanding the increase of cardiac risk observed in elderly. The aim of the study is to evaluate the relationship between obstructive sleep apnea severity, age, gender and heart rate response associated with obstructive sleep apnea. Drug-free patients diagnosed with obstructive sleep apneas were included. Clinical data and 24-h polysomnography recordings were analyzed.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Restless legs syndrome patients
• Hospital routine for sleep disorders breathing diagnosis
• Apnea index > 0

Exclusion criteria

• Narcolepsy-cataplexy
• Sleep irregularities and sleep deprivation symptoms
• Lack of neurological or psychiatric diseases
• Periodic leg movements
• Central sleep apnea, treatment
• Cerebral lesion
• Medical illness
• Medication or drinks affecting sleep and wake state.

Trial design

60 participants in 1 patient group

patients with obstructive sleep apneas

Treatment:

Device: standard 24-h ambulatory polysomnography