Care Pathways and Disparities in Care for Older Patients With Cancer: Typology, Determinants and Effect on Prognosis ( PASSAGE )

Assistance Publique - Hôpitaux de Paris

Status: Active, not recruiting

Conditions: Geriatric Assessment; Causality; Health Services Research; Cancer; Tumor; Aged

Study type: Observational

Funder types: Other

Identifiers

NCT07092800

CSE-24-08_PASSAGE (Other Identifier)

APHP240996

Details and patient eligibility

About

More than half of new cases of cancer in Europe in 2022 occurred in people aged over 70. In addition to cancer, the majority of older people have one or more illnesses that may interact with the treatment decision, cancer progression, tolerance and efficacy of treatments, quality of life, care pathway and survival. Furthermore, cancer treatments are most often evaluated in middle-aged subjects without severe disease, so the real-life management of older patients is often empirical.

The general objective of the PASSAGE project is to assess the hospital care pathways of older patients with cancer treated at AP-HP by evaluating key elements of these pathways from both geriatric and therapeutic perspectives. Characterizing these care trajectories will help identify the most vulnerable patient profiles and potential disparities in access to care, with the goal of optimizing the management of elderly patients with cancer.

The aims of this research are 1) to provide a better description of trends in the management of older cancer patients in routine clinical practice, and 2) to assess the impact of frailty, multimorbidity and the management of these patients on the prognosis of the disease.

Enrollment: 75,000 estimated patients

Sex: All

Ages: 70 to 130 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 70 or over,
• Having at least one International Classification of Disease, 10th revision (ICD-10) for solid cancer recorded as principal diagnostic or related,
• During treatment in an AP-HP hospital,
• Between 01/08/2017 and 31/07/2023.

Exclusion criteria

• opposition to the reuse of healthcare data

Trial design

75,000 participants in 1 patient group

Patients aged 70 or over with solid cancer

Description:

The following inclusion criteria will be applied to identify the study population: * Patients aged 70 or over, * Having at least one International Classification of Disease, 10th revision (ICD-10) code for solid cancer recorded as principal diagnostic or related, * During treatment in an AP-HP hospital, * Between 01/08/2017 and 31/07/2023.