Caries Prevention Potential of Pearl Powder Versus CPP-ACP on Enamel White Spot Lesions

Ruba Alaa El Din Adel El Damarisy

Status and phase: Unknown; Phase 2

Conditions: White Spot Lesion of Tooth

Treatments: Other: pearl powder; Drug: CPP-ACP

Study type: Interventional

Funder types: Other

Identifiers

NCT03973554

11090 (Registry Identifier)

Details and patient eligibility

About

to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel white spot lesions.

Full description

The aim of the study is to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel White Spot Lesions using laser fluorescence device scoring from 0 to 99, with daily application time of 3 months and follow up period of 6,9,and 12 months.

Enrollment: 58 estimated patients

Sex: All

Ages: 12 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• good oral hygiene
• cooperative patient
• completion of orthodontic therapy
• presence of at least two white spot lesions on the labial surface of six maxillary anterior teeth, that were not present before orthodontic treatment

Exclusion criteria

• bad oral hygiene
• lack of patients compliance
• allergy to milk products
• pregnant or lactating women
• presence of dentin caries, restorations, or enamel hypoplasia on maxillary anterior teeth
• presence of periodontal pockets around maxillary anterior teeth

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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58 participants in 2 patient groups

pearl powder

Experimental group

Description:

natural product, support bone and joint health

Treatment:

Other: pearl powder

CPP-ACP

Active Comparator group

Description:

product for professional use containing the active ingredient (CPP-ACP), a special milk-derived protein that has a unique ability to release bio-available calcium and phosphate to tooth surfaces.

Treatment:

Drug: CPP-ACP