Carotid Artery Corrected Flow Time as a Predictor of Hypotension After Induction of General Anesthesia in Elderly Patients

Fujian Medical University (FJMU)

Status: Completed

Conditions: General Anesthesia Induction for Elective Surgery

Treatments: Procedure: ultrasonographic measurement of carotid artery corrected flow time (FTc)

Study type: Observational

Funder types: Other

Identifiers

NCT05628051

2022XHYG0018-01

Details and patient eligibility

About

The number of elderly patients undergoing elective surgery has been growing in recent years. Elderly patients often have a variety of underlying diseases, including hypertension, coronary heart disease, diabetes, arteriosclerosis, etc., which increase the risk. When the elderly receive general anesthesia, hypotension often occurs after anesthesia induction. Once hypotension occurs, it may lead to myocardial ischemia, myocardial infarction, stroke and other serious complications. Therefore, in clinical anesthesia, a simple, quick and accurate prediction method is needed to evaluate and predict the risk of hypotension in elderly patients after induction, so that appropriate intervention measures can be taken in advance to reduce the incidence of hypotension in elderly patients after induction, thus reducing the occurrence of related complications and ensuring the safety of anesthesia and surgery.Carotid Artery Corrected Flow Time（FTc） is a recently developed volumetric predictor, which refers to the time between the the onset of systolic flow until the closure of the aortic valve. It is related to cardiac preload and can reflect cardiac output to a certain extent. It is considered as a reliable indicator for evaluating volume status and volumetric reactivity. Therefore, this study assessed the effect of FTc combined with perioperative fluid therapy on preventing hypotension after general anesthesia induction in elderly patients.

Enrollment: 177 patients

Sex: All

Ages: 65 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who received elective surgery under general anesthesia, aged 65-85 years old, gender unlimited, ASAI-II

Exclusion criteria

• uncontrolled hypertension
• unstable angina pectoris
• history of myocardial infarction
• after heart stent implantation
• severe arrhythmia：Atrial fibrillation、Ventricular premature beat, frequent atrial premature beat, other non-sinus rhythm
• pacemaker implants
• cardiomyopathy
• a left ventricular ejection fraction of < 40%
• history of neck trauma and surgery
• BMI>30

Trial design

177 participants in 2 patient groups

Hypotension after anesthetic induction group

Description:

Patients with hypotension after anesthetic induction

Treatment:

Procedure: ultrasonographic measurement of carotid artery corrected flow time (FTc)

Non-hypotension after anesthetic induction group

Description:

Patients without hypotension after anesthetic induction

Treatment:

Procedure: ultrasonographic measurement of carotid artery corrected flow time (FTc)