Carotid Plaque-Burden Scale and Outcomes. A Real Life Study

Fundación para la Formación e Investigación de los Profesionales de la Salud de Extremadura

Status: Completed

Conditions: Atheroscleroses, Cerebral; Carotid Plaque

Study type: Observational

Funder types: Other

Identifiers

NCT06187532

1122023

11223 (Registry Identifier)

Details and patient eligibility

About

Carotid ultrasonography has been proposed as a tool for prediction of future cardiovascular disease (CVD). Nevertheless, its role in clinical practice remains controversial.

Methods: The investigators analyse the incidence of CVD and mortality in a cohort of 1004 participants without preexisting CVD according to a simple plaque scale recorded in different segments of the carotid artery assess by ultrasound. A prognostic tool for CV events was development adding Carotid Plaque-Burden (CPB) scale to the Systematic COronary Risk Evaluation (SCORE2) table (CPB- SCORE2 scale).

Full description

Based in number of plaques and stenosis a simple plaque scale was recorded in different segments of carotid artery, involving a cohort of 1004 participants with vascular risk factors. Outcomes were recorded during 14 years. A prognostic tool for CV events was development adding simple Carotid Plaque-Burden (CPB) scale to the SCORE2 table (CPB- SCORE2 scale).

Enrollment: 1,004 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any of these vascular risk factors: Total cholesterol >200 mg/dL, hypertension, or diabetes, or receiving medication for them
• No cardiovascular disease: coronary, cerebral o peripheral arterial disease.

Exclusion criteria

• Associated conditions: cancer, heart failure, chronic obstructive disease, renal insufficiency, neurodegenerative diseases, rheumatic diseases or chronic infections.
• Neck anatomical barriers to perform ultrasound.
• Enrolled in a clinical trial.
• Attend <70% of regular appointments