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Carpal Bone Erosion in Rheumatoid Arthritis :Diagnostic Value

S

Sohag University

Status

Not yet enrolling

Conditions

Rheumatoid Arthritis

Treatments

Radiation: musculoskeletal ultrasound

Study type

Observational

Funder types

Other

Identifiers

NCT06562049
soh-med-24-07-10MS

Details and patient eligibility

About

Rheumatoid arthritis (RA) is a systemic inflammatory disease characterized by proliferative hyper vascularized synovitis which primarily affects synovial joints. Synovium of bursa; tendon sheaths; attachment sites of cartilage, ligament, and tendons to the bone; soft tissue; and bones can be mentioned among the other areas under influence of RA. Changes happen to be symmetrical and may present as fusiform soft tissue swelling, regional osteoporosis, marginal-central erosions, cartilage damage, joint destruction, narrowing of joint space and fibrous ankyloses. Wrist, metacarpophalangeal and metatarsophalangeal joints are the first sites to be affected .Over the past few years, an increasing number of rheumatologists have started to use US in the clinical setting of the early arthritis clinic. While US allows for an accurate and non-invasive multisite assessment of joint involvement in patients with RA, time for US examination is not infinite

Enrollment

110 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

    1. RA patients fulfilled the 2010 American College of Rheumatoid Arthritis classification criteria.[8] 2. SLE patients fulfilled the 2019 ACR\EULAR classification criteria for SLE.[9] 3. Age above 18 years old. 4. Patient cooperative and can answer questions. 5. Patients who are able and willing to give written informed consent.

Exclusion criteria

    1. Age below 18 years and above 60 years. 2. Uncooperative patients. 3. Patient not able and willing to give written informed consent.

Trial design

110 participants in 3 patient groups

cases
Description:
rheumatoid arthriris patients
Treatment:
Radiation: musculoskeletal ultrasound
control
Description:
systemic lupus patients
Treatment:
Radiation: musculoskeletal ultrasound
controls
Description:
healthy controls
Treatment:
Radiation: musculoskeletal ultrasound

Trial contacts and locations

1

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Central trial contact

ahmed M mahrous, Professor; abeer A abdelaal, Resident

Data sourced from clinicaltrials.gov

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