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Carpal Tunnel Syndrome, Right/Left Judgement

B

Bozyaka Training and Research Hospital

Status

Completed

Conditions

Carpal Tunnel Syndrome

Treatments

Diagnostic Test: Montreal Cognitive Assessment Test
Diagnostic Test: Nerve conduction study

Study type

Observational

Funder types

Other

Identifiers

NCT04967144
2021/40

Details and patient eligibility

About

The discrimination of the right/left side of the body is related to the integrity of the motor and somatosensory areas at the cortical and subcortical levels. Although some studies have shown that there may be an effect on the right/left representation at the cortical and subcortical levels in cases that cause severe neuropathy and neuropathic pain, this effect has not been proven in milder neuropathies. In this study, the effect on right/left side discrimination will be investigated even in cases with carpal tunnel syndrome. Additionally, the investigators aimed to assess the relationship between right/left discrimination and symptom severity.

Full description

The left/right discrimination is a motor imagery task that involves viewing images of a body part and determining whether each image belongs to the left or right side of the body or if it rotates towards it. Some studies have shown that there may be an effect on the right/left representation at the cortical and subcortical levels in cases that cause severe neuropathy and neuropathic pain, this effect has not been proven in milder neuropathies, such as carpal tunnel syndrome. In this study, the relationship between right/left decision accuracy will be compared with control subjects. The investigators will assess the relationship between right/left judgment and symptom severity, two-point discrimination, and handgrip force.

The hypothesis of the study are:

  1. The right/left discrimination accuracy is less than the control subjects.
  2. Right/left discrimination is in relationship with symptom severity, two-point discrimination, and handgrip force.

Enrollment

200 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Participants with a duration of symptoms associated with unilateral CTS of at least 3 months
  • Participants with clinically and nerve conduction study confirmed carpal tunnel syndrome
  • All participants will be right-hand dominance and diagnosed with carpal tunnel syndrome on the same side
  • Participants with MOCA score minimum 26.

Exclusion criteria

  • Severe visual impairment that may prevent performing the test
  • Polyneuropathy
  • Cervical spine surgery history
  • Presence of abnormal cervical spine, shoulder, and elbow joint examination findings
  • Patients with any history of surgery for the upper extremity
  • Congenital/Developmental upper extremity malformations
  • Central nervous system disease
  • Antihistaminic, gabapentinoids, antiepileptics, methylphenidate, modafinil, neuroleptics use

Trial design

200 participants in 2 patient groups

Carpal Tunnel syndrome
Description:
.Patients with carpal tunnel syndrome
Treatment:
Diagnostic Test: Montreal Cognitive Assessment Test
Diagnostic Test: Nerve conduction study
Control subjects
Description:
Healthy subjects
Treatment:
Diagnostic Test: Montreal Cognitive Assessment Test
Diagnostic Test: Nerve conduction study

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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