Case-Control Study to Identify Risk Factors for Microscopic Colitis

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Lymphocytic Colitis; Collagenous Colitis; Microscopic Colitis

Treatments: Other: Whole saliva sample

Study type: Observational

Funder types: Other

Identifiers

NCT01928667

NL44127.068.13

Details and patient eligibility

About

The purpose of the study is to assess among others environmental and hygiene-related risk factors for microscopic colitis (MC), a common diarrheal disease.

Enrollment: 487 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Confirmed Diagnosis of MC (CC or LC) between January 1, 2000 and December 31, 2012.
• Inhabitant of the province of Limburg or the Eindhoven region at the moment of diagnosis

Exclusion criteria

• Below 18 years of age at the time of diagnosis
• Not capable of signing an informed consent
• Deceased at moment of approximation

Trial design

487 participants in 2 patient groups

Microscopic Colitis

Description:

Group consists of subjects diagnosed with either collagenous of lymphocytic colitis between January 1, 2000 and December 31, 2012

Treatment:

Other: Whole saliva sample

Healthy Controls

Description:

Control group consists of subjects with no history of microscopic colitis. Group is age and sex matched with the case-group

Treatment:

Other: Whole saliva sample