Catechin Mouth-washing for Removal of Intraoral Bacteria

Masahiro Morikawa

Status

Terminated

Conditions

Elderly

Treatments

Dietary Supplement: catechin extracts

Study type

Interventional

Funder types

Other

Identifiers

NCT00377507

CT2006004

Details and patient eligibility

About

The Purpose of this study is to evaluate the effects of catechin mouth-washing on the removal of intraoral bacteria in the elderly

Full description

Catechins are the major components of tea flavonoids and recent in vitro experimental studies have revealed that tea catechin extracts induce bactericidal effects. However, a limited number of studies have been conducted on the clinical effects of tea catechin against bacterial infection and also the effects in the elderly is unclear. Based on these backgrounds, we designed a prospective randomized controlled study to evaluate the effects of catechin mouth washing on oral pathogenic bacterial detected in the elderly.

Enrollment

36 patients

Sex

All

Ages

65 to 95 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

aged over 65 years
detected oral pathogenic bacterium and revalidated during the wash-out period
without antibacterial medicine, other mouth-washing remedies during the study
Obtained written informed consent before participation

Exclusion criteria

possessing some infectious diseases in need of therapy
possessing tea or catechin allergy
diagnosed as inadequate for other reasons to participate the study by principal investigator