Catheter Ablation of Ventricular Arrhythmia Reduces Skin Sympathetic Activity

Mayo Clinic

Status: Terminated

Conditions: Ventricular Tachycardia

Study type: Observational

Funder types: Other

Identifiers

NCT04837183

20-001448

Details and patient eligibility

About

This study is being done to determine whether there is an increase in sympathetic nerve activity before the onset of ventricular arrhythmias or irregular heartbeat rhythm. In addition, this study is looking at the relationship between sympathetic nerve activity and how patients with ventricular arrhythmias respond to catheter ablation treatment.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who have non-sustained or sustained VA (VA ≥ 30s or receiving appropriate ICD therapies) are presented to the clinic or admitted to the hospital within 7 days of episodes.
• The causes of VA are associated with structural heart diseases including ischemic or nonischemic cardiomyopathy (idiopathic cardiomyopathy, hypertrophic cardiomyopathy, cardiac sarcoidosis or amyloidosis, and arrhythmogentic right ventricular dysplasia).
• Subjects are 18 years of age and older.

Exclusion criteria

• Female patients who is pregnant or of childbearing potential and not on a reliable form of birth control.
• Allergic to skin patch electrodes.
• Vulnerable populations (fetuses, neonates, pregnant women, prisoners, institutionalized individuals).