Causal Relationship Between Dry Eye and Accommodative Spasm

Far Eastern Memorial Hospital

Status: Enrolling

Conditions: Dry Eye

Treatments: Device: presbyopia glasses

Study type: Observational

Funder types: Other

Identifiers

NCT05120401

110100-E

Details and patient eligibility

About

To investigate the causal relationship of Sicca dry eye patients with presbyopic refractive error and accommodative spasm.

Full description

Dry eye is a disease of the ocular surface. Severe dry eye produce symptom of discomfort in and around the eye that drastically affect life quality of the patient. OSDI index is retrieve from a questionnaire specific for these dry eye symptoms, it is an internationally accepted level to reveal the severity of Dry eye disease. One part of the symptom is pain and soreness around the eye. Hyperalgesia is an increase response to a stressful/ noxious stimulus whereas allodynia is a painful response to a normally innocuous stimulus. Our hypothesis state that Sicca Dry eye upregulated inflammatory cytokine in the eye has pre-sensitized the nociceptor nerve fiber in the cornea and orbit, therefore the normally innocuous effort of accommodation and ciliary muscle contraction produce intolerable retro-orbital eye pain, which drives the patient to seek medical attention, on presentations these patient show an elevated OSDI and Pain Index (PI).

Enrollment: 200 estimated patients

Sex: All

Ages: 20 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• dry eye

Exclusion criteria

• under 20 year old

Trial design

200 participants in 2 patient groups

dry eye with presbyopia

Description:

dry eye with presbyopia , Intervention : glasses prescrubed

Treatment:

Device: presbyopia glasses

dry eye with presbyopia without glasses use

Description:

no glasses use

Treatment:

Device: presbyopia glasses