Causes of Mortality in Kidney Transplant Recipients (Paradigme)

University Hospital, Strasbourg, France

Status: Enrolling

Conditions: Renal Disease

Study type: Observational

Funder types: Other

Identifiers

NCT05529186

8558

Details and patient eligibility

About

The causes of mortality in kidney transplant patients and the risk factors for mortality have been widely published. However, there is a high variability according to geographical areas and time. Recent studies suggest that the classical hierarchy of causes of mortality, i.e. the predominance of cardiovascular causes of death, could be overturned by the increase in infectious and cancer-related deaths. Investigators will try to highlight this paradigm shift and the related risk factors by studying two large French transplantation databases.

Enrollment: 7,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult subject (≥18 years old) during transplantation
• Transplantation performed between 01/01/2008 and 31/12/2014
• Kidney transplant subject, double transplants kidney + pancreas, or kidney + islets of Langherans
• Subject previously transplanted other organs
• Subject not objecting, after being informed, to the reuse of their data for the purposes of this research

Exclusion criteria

• Subject who expressed their opposition to participating in the study
• Subject having received a double transplant during the same operation: kidney + heart, kidney + liver, kidney + lungs