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Caval Aorta Index for Fluid Optimization in Traumatic Brain Injury (CAI for fluids)

M

Mansoura University

Status

Not yet enrolling

Conditions

Fluid Balance

Treatments

Other: control group
Procedure: ultrasound measurement of caval aorta index

Study type

Interventional

Funder types

Other

Identifiers

NCT06940258
Caval aorta index

Details and patient eligibility

About

Traumatic brain injury is a leading cause of death and disability in trauma patients. As the primary injury cannot be reversed; management strategies must focus on preventing secondary injury by avoiding hypotension and hypoxia besides, maintaining appropriate cerebral perfusion pressure, which is a surrogate for cerebral blood flow.

Full description

The caval aorta index is an ultrasound element, relatively new, used to assess volume status. Technically, the sonographic assessment of the inferior vena cava /aorta diameter ratio is an easy test to perform and can be performed effectively by doctors who are not experienced in the field of sonography (Kusumastuti et al .2021).

In this study; the caval aorta index will be used to guide fluid dosage in critically ill patients with traumatic brain injury.

Enrollment

92 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Traumatic brain injury diagnosed by computed tomography scan Glasgow coma score ≥ 4

Exclusion criteria

Inability to get consent. Pregnant and lactating women Traumatic subarachnoid hemorrhage Spinal cord injury Increased intra-abdominal pressure Abdominal aortic aneurysm Inferior vena cava (IVC) thrombus Portal hypertension Acute corpulmonale Congestive heart failure chronic hemodialysis Surgical intervention other than neurological one within the first 7 days Mechanical ventilation need during first 7 days Cardiac arrest during the first 7 days

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

92 participants in 2 patient groups

Control group
Other group
Treatment:
Other: control group
ultrasound-guided caval-aorta index group
Experimental group
Treatment:
Procedure: ultrasound measurement of caval aorta index

Trial contacts and locations

0

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Central trial contact

Maha Ahmed Abozeid, Assistant Professor

Data sourced from clinicaltrials.gov

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