CBCR for Executive Functions in Patients With ABI in the Chronic Phase

Katrine Sværke

Status: Completed

Conditions: Cognitive Symptom; Acquired Brain Injury; Executive Dysfunction

Treatments: Behavioral: Computer based cognitive rehabilitation; Other: Sham computerized gaming

Study type: Interventional

Funder types: Other

Identifiers

NCT03558308

H-18006890

Details and patient eligibility

About

This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury

Full description

This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury using two clinically developed programmes and one sham-intervention. Furthermore, the study consists of Groups that receives the computerized training both with and witouth support from a professional.

Enrollment: 72 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Persons who are able to give an informed consent both verbally and in writing
• Persons in the chronic phase after stroke or traumatic brain injury (more than one year post onset)
• Persons who score less than the 30. Percentile in one or more of the primary outcome measures outlined above.

Exclusion criteria

• Persons with neurodegenerative diseases
• Persons with diseases which can influence executive functions such as ADHD
• Persons who are motorically or cognitively unable to use a tablet and complete the CBCR-training

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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72 participants in 4 patient groups

Brain+ with clinical support

Experimental group

Description:

Intervention: Computer based cognitive rehabilitation. This group will train with the programme 'Brain+' and receive continuous support from a clinician during the intervention period.

Treatment:

Behavioral: Computer based cognitive rehabilitation

Cogmed with continuous support

Experimental group

Description:

Intervention: computer based cognitive rehabilitation. This group will train with the programme 'Cogmed' and receive continuous support from a clinician during the intervention period.

Treatment:

Behavioral: Computer based cognitive rehabilitation

Brain+ without support

Experimental group

Description:

Intervention: computer based cognitive rehabilitation. This group will train with the programme 'Brain+' but receive no support during the intervention period.

Treatment:

Behavioral: Computer based cognitive rehabilitation

Sham-training group

Sham Comparator group

Description:

Intervention: Sham computerized gaming. This group will train computerized solitaire and other computerized games which are thought to be generally cognitive stimulating but with a very limit load on executive functions. This group will receive continuous support during the intervention period.

Treatment:

Other: Sham computerized gaming