CBD, Nutrient Metabolism and Energy Intake

Loughborough University

Status

Completed

Conditions

Appetitive Behavior

Lipid Metabolism Disorders

Glucose Metabolism Disorders (Including Diabetes Mellitus)

Treatments

Dietary Supplement: Acute oral CBD supplementation

Dietary Supplement: Acute oral placebo supplementation

Study type

Interventional

Funder types

Other

Identifiers

NCT05618756

5553

Details and patient eligibility

About

CBD may affect metabolic control and energy intake. However, there is currently little data regarding these specific outcomes in humans. Therefore, this study will investigate whether a single 300 mg dose of CBD can improve metabolic control following a meal and/or reduce energy intake at a subsequent meal. Healthy, adult volunteers will complete two conditions in a crossover design, comparing outcomes following both CBD and placebo supplementation.

Enrollment

15 patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

• Self-report as healthy, male or female, aged 18-50, body mass index ≥18.5 and <30.0

Exclusion criteria

Currently engage in >10 hours moderate or vigorous intensity physical activity per week
Have consumed CBD or cannabis at all within the past two months
Have used CBD or cannabis regularly (>2x in a week) within the past four months
Are suffering from any clinically significant illness
Have regularly used tobacco within the previous 6 months (> 2/week)
Currently use any prescription or over-the-counter medications (except for hormonal contraception and simple painkillers)
Have given a standard blood donation within 30 days of screening
Are currently pregnant or lactating
Are allergic/intolerant to any ingredients in food items provided during the study