CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies

University of Washington

Status: Completed

Conditions: Schizophrenia; Psychosis; Bipolar Disorder; Schizo Affective Disorder; Depressive Disorder

Treatments: Behavioral: CBTpro

Study type: Interventional

Funder types: Other; Industry; NIH

Identifiers

NCT05127837

5R42MH123215-02 (U.S. NIH Grant/Contract)

STUDY00014706

Details and patient eligibility

About

The primary objective of this grant is to develop and evaluate an Artificial Intelligence-based clinical training tool--CBTpro--to support high-quality skills training in CBT for psychosis (CBTp). CBTpro will provide a rapid means of scaling and sustaining high-quality CBTp in routine care settings across the US.

Full description

This fast-track Small Business Technology Transfer (STTR) grant is a partnership between the University of Washington and private company LYSSN that includes the development and iterative testing of CBTpro, a Computerized Clinician Support Tool designed to teach behavioral health providers and students Cognitive Behavioral Therapy for psychosis (CBTp). CBTpro uses natural language processing to provide automated speech-to-text and machine learning to score trainee's responses to simulated patients with psychosis.

Once technical reliability of the tool is achieved through iterative modifications based on usability and field trials, a randomized control trial will be conducted to assess CBTpro training vs. training as usual with N=100 providers / N=300 clients on clinician skills and client outcomes.

Enrollment: 379 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Client Inclusion: Adults who speak English, meet with their provider who is participating in the study at least bi-weekly (2x a month), and do not plan to leave services in the next 6 months. Qualifying diagnoses for clients include: schizophrenia; schizoaffective disorder; schizophreniform disorder; delusional disorder; other specified schizophrenia spectrum and other psychotic disorder; unspecified schizophrenia spectrum or other psychotic disorder; bipolar disorder with psychotic features; major depressive disorder with psychotic features

Exclusion criteria: Dx of psychosis secondary to substance intoxication

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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379 participants in 2 patient groups

Treatment as Usual (TAU)

No Intervention group

Description:

CBT for psychosis distance learning course.

CBTpro

Experimental group

Description:

In addition to TAU, clinicians and clients receive the CBTpro training.

Treatment:

Behavioral: CBTpro