CD49 in Optimization The Cologenicity of Mesenchymal Stem Cell Culture Passage

Sohag University

Status: Unknown

Conditions: Umbilical Cord of Normal Labor

Treatments: Device: flow cytomery

Study type: Observational

Funder types: Other

Identifiers

NCT05093725

Soh-med-21-10-01

Details and patient eligibility

About

Human mesenchymal stem cells (MSCs) due to their regenerative and immunomodulatory properties are widely used for the treatment of bone and cartilage damage, cardiovascular, gastrointestinal, autoimmune, neurodegenerative diseases and cancer .It is shown that the use of MSCs in therapy is safe and can be effective .In 2006, the International Society for Cellular Therapy (ISCT) proposed the minimal criteria to define human MSCs. First, MSCs must be plastic-adherent when maintained in the standard culture conditions. Second MSCs must express CD105, CD73 and CD90, and lack expression of CD45, CD34, CD14 or CD11b, CD79a or CD19 and HLA-DR surface molecules.

Enrollment: 10 estimated patients

Sex: All

Ages: 1+ day old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

normal babies delivered by normal labor

Exclusion criteria

diseased or congenital anomalies