Cefazolin Dosing in Children Undergoing Cardiac Surgery With Cardiopulmonary Bypass (CEFA)

Ghent University Hospital (UZ)

Status: Completed

Conditions: Cardiopulmonary Bypass

Treatments: Procedure: blood and tissue sampling

Study type: Observational

Funder types: Other

Identifiers

NCT02749981

2012/631-632-633

Details and patient eligibility

About

Pharmacokinetics of cefazolin in children undergoing cardiac surgery.

Enrollment: 56 patients

Sex: All

Ages: Under 15 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pediatric patients undergoing cardiac surgery with cardiopulmonary bypass
• minimum weight 1.8 kg
• intra-arterial or intravenous access other than the drug infusion line available for blood sampling (arterial line is preferred)

Exclusion criteria

• no catheter in place for blood sampling
• absence of parental/patient consent
• known hypersensitivity to cefazolin

Trial design

56 participants in 1 patient group

Cefazolin

Description:

patients receiving cefazolin as part of routine clinical care

Treatment:

Procedure: blood and tissue sampling