Celiac Disease and Quality of Life in Children and Adolescents (CeliaQLife)

University of Oslo (UIO)

Status: Enrolling

Conditions: Quality of Life; Celiac Disease in Children; Nutritional Deficiency

Study type: Observational

Funder types: Other

Identifiers

NCT06568263

591377

Details and patient eligibility

About

Celiac disease is a disorder commonly diagnosed during childhood. The treatment is a lifelong gluten-free diet. Both the condition and the diet can influence the children's physical and emotional well-being.

The main goal of this observational study is to learn about nutritional status in a group of children with celiac disease compared to a group of healthy children.

The nutritional assessment includes information on diet, biochemical measurement, and body composition. Quality of life will also be assessed.

The study can contribute to ensure good health and well-being in children on a gluten-free diet.

Full description

• A 24-hour dietary recall will be done by a clinical dietician to assess intake of energy and micro- and macronutrients.
• Blood will be drawn for assessment of vitamin- and mineral status.
• Feces and urine samples will be collected to measure gluten immunogenic peptides (GIP) to assess exposure to gluten.
• A self-developed interview will be used for assessment of adherence to the gluten-free diet and compared with the results from a 11-item questionnaire.
• Weight and height will be measured.
• Bone mineral density and body composition will be measured by dual-energy x-ray absorptiometry (DXA).
• Health-related quality of life (QOL) will be measured by the PedsQL.

Enrollment: 160 estimated patients

Sex: All

Ages: 6 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• eating a regular diet

Exclusion criteria

Trial design

160 participants in 2 patient groups

Celiac disease

Description:

Children diagnosed with celiac disease on a gluten-free diet

Healthy

Description:

Healthy children on a regular diet