Cell Based Non Invasive Prenatal Testing as an Alternative to Chorionic Villus Sampling Following Preimplantation Genetic Testing

Aalborg University Hospital

Status: Completed

Conditions: Prenatal Diagnoses; Preimplantation Genetic Diagnosis

Treatments: Procedure: Cell-based non-invasive prenatal testing

Study type: Interventional

Funder types: Other

Identifiers

NCT04584047

N-20180001

Details and patient eligibility

About

The study aims to investigate whether cell-based non-invasive prenatal testing (cbNIPT) can be used as an alternative to invasive chorionic villus sampling (CVS) in patients who achieve pregnancy following preimplantation genetic testing for monogenic disorders (PGT-M).

Enrollment: 8 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Achieved pregnancy following preimplantation genetic testing

Exclusion criteria

• None

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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8 participants in 1 patient group

Intervention group

Experimental group

Description:

This arm has blood collected either at the time of CVS.

Treatment:

Procedure: Cell-based non-invasive prenatal testing